BlogEverything you wanted to know about Calmare treatment

scrambler therapy for neuropathy treatment

Scrambler therapy has proved to be highly effective for treating chronic neuropathy pain as well as cancer pain in patients who are resistant to other forms of treatment. One of the main advantages of Calmare scrambler therapy is that it is non-invasive, medicament-free and painless, and thus recommended for treating pain in a wide number of neuropathic conditions.

To understand how scrambler therapy helps in neuropathy pain treatment, we will take a look at how mechanism of pain transmission and perception work. A commonly accepted and long standing model that explains this process is called Gate control theory. It has been introduced in 1965, and with certain updates, redefinitions and revisions it is still relevant to this day. It suggests that the pain signals have to pass through ‘nerve gates’ at the spinal cord level and before they can reach the brain, they need to get cleared. How the pain signals are treated at the nerve gates is determined by several factors:

- their intensity

- the intensity of complementing sensory signals such as pressure, touch, temperature, if they are present at the injury site

- whether the brain itself sends pain signals or not


How Scrambler Therapy treats neuropathic pain


One of the typical characteristics of chronic neuropathic pain is abnormal functioning of the somatosensory nervous system, which made putting gate control theory into practice through treatments – rather difficult

In acute pain however, where there is a clear cause-effect relationship, the gate control theory is easily confirmed by experiments, and consistent.

It gives a context in which pain as such can be interpreted as an information, while chronic pain can be interpreted as an information-governed pain system modification.

Thus, the approach of Calmare scrambler therapy is not to inhibit the pain transmission, but to use the same pathways to transform it into a ‘non pain’ information.

In short, it uses information (signal) as the central point of control of the whole pain system, both in creation of chronicity and in its regression. Theoretical expectation of Calmare scrambler pain treatment is that it offers immediate analgesic effect and, after repeated cycles of treatment, recovery of normal physiological responses.

The Calmare scrambler machine produces 5 artificial neurons, made both safe and effective by a complex algorithm. These neurons, similarly to regular neurons that receive, process and transmit information, perform these same functions by using specifically designed hardware and software. The hardware is engineered to receive the information from the algorithm which creates ‘non pain’ strings and transforms them into the flows of fabricated action potentials, fully compatible with the endogenic ones in functionality. The emission that follows as a result, synchronizes the C fibers surface receptors that will continue to distribute the information that has been generated by artificial neurons.

Pain scrambler therapy has resulted in pain relief in more than 80% of cases, typically after 2-months follow-up treatments. The clinical testing and trials observed no substantial side effects.

Calmare scrambler therapy that we provide in Baltimore Ketamine Clinic, successfully treats pain in the following conditions: Chemotherapy induced neuropathy (CIPN), back pain, sciatica, post-surgical neuropathic pain, phantom limb syndrome, postherpetic neuralgia, intractable cancer pain, brachial plexus pain, CRPS (RSD), post-surgical nerve lesion neuropathy, trigeminal neuralgia, temporomandibular joint disorder (TMJ), fibromyalgia, diabetic neuropathy and pudendal neuropathy.

If you are suffering from any of the above chronic pain conditions, do not hesitate to contact us and schedule a consultation.

Site Search

Contact Info

Contact us

Are you suffering from chronic pain? Reach out to schedule a consultation for a modern pain therapy solution.


Calmare Maryland
909 Ridgebrook Road
Unit 202 Sparks, MD 21152

Working hours

Monday - Friday
9:00am - 4:00pm


[email protected]